It’s been a long wait for fans of the 2006 cult film Children of Men, but acclaimed director Alfonso Cuarón is finally set to debut his follow-up. The film is Gravity, starring George Clooney and Sandra Bullock as astronauts on a routine Space Shuttle mission. The newly released trailer sets up the plot: Clooney and Bullock are in the midst of a spacewalk 372 miles above earth when disaster strikes. The shuttle is destroyed, and the two astronauts are left stranded in the vast emptiness of space, tethered only to each other. Check out the trailer below, and look for Gravity to hit theaters October 4th.